Immediate hemodynamic response of patients with atrioventricular block and cardiac failure to transvenous pacing.

Immediate hemodynamic improvement in patients with complete heart block occurs when the ventricular rate is increased by electrical pacing. During pacing, there is reduction in the pulmonary artery wedge, right atrial, and left and right ventricular filling pressures. The mean rate of ejection, stroke volume, and stroke work decreased following pacing, whereas the ejection time per minute increased, and dye curves assumed a more normal configuration. Very little change was noted in the resting cardiac output. The paced heart is able to obtain greater increases in cardiac output, stroke volume, and mean rate of ejection during exercise than when unpaced. In addition, pacing tends to return elevated exercising filling pressures in the right and left ventricles toward normal.